Dissecting the Regulation of Nephron Progenitor Identity, Self-Renewal and Commitment at a Single Cell Level

Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk

AN Combes, B Phipson, KT Lawlor, A Dorison, R Patrick, L Zappia, RP Harvey, A Oshlack, MH Little

2019-06-01

Recent advances in the generation of kidney organoids and the culture of primary nephron progenitors from mouse and human have bee..

Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

AN Combes, L Zappia, PX Er, A Oshlack, MH Little

2019-01-23

Background: Human kidney organoids hold promise for studying development, disease modelling and drug screening. However, the utili..